The home side took the lead in the second half in the 59th minute through Ciprian Deac after a goalless first half.
Moroccan forward Youssef En Nesyri scored the equaliser in the 82nd minute to give the Spanish side an important away goal.
The result is a reflection of Sevilla’s poor run form as they have only managed three draws and two losses while CFR Cluj has three draws and one draw and a loss.
The second leg will come up in Spain on the 27th of February at the Estadio Ramon Sanchez Pizjuan.
In other games involving Spanish sides, Getafe beat Dutch giants Ajax 2-0, Brazilian forward Deyverson scored in the 38th while compatriot Kennedy scored his team’s second in stoppage time to give Getafe a huge 2-goal cushion to take to the Netherlands next Thursday.
Meanwhile, Españyol lost scandalously 4-0 to English Premier League side Wolves at the Molineux Stadium.
Diogo Jota scored a Hattrick while fellow Portuguese Reuben Neves scored once in the second half.
The striker’s first of his three came in the 15th through a Raul Jimenez assist, and he scored the second in the 67th minute after Raul Jimenez’s goal in the 52nd minute of the second half.
His last 81st minute through a Joao Mouthino assists making the return game on Thursday a big mountain to climb.
In Greece, Alexander Lacazette scored the Gunners’ only goal as they pipped Olympiacos to a 1-0 win.
German side Frankfurt beat Austrian side RB Salzburg beat 4-1 while Roma beat Gent 1-0, Wolfsburg 2-1 Malmo, Bayer Leverkusen 2-1 Porto, Shakhtar Donetsk beat Benfica 2-1.
In the Netherlands, AZ Alkmaar drew 1-1 LASK Linz and Inter beat Ludogorets 2-0 amongst some of the results.
Written by: Daniel Ademiju Idowu
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